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HEPATITIS
PROFILE (A+B+C)
HEPATITIS A
Hepatitis A
is a communicable, contagious disease that spreads from person to person. It
is estimated there are between 84,000 and 134,000 total infections per year
in the United States.
Hepatitis A
virus can be transmitted through oral-anal sex.
Blood tests, widely
available, can accurately detect the body response to the presence of
hepatitis A.
About 2
persons in 1000 with symptoms of acute hepatitis A will die of acute liver
failure. Hepatitis A may cause no symptoms at all when it is contracted,
especially in young people. When symptoms are present they appear as sudden
onset of an influenza-like illness.
The direct
and indirect costs of Hepatitis A exceed $300 million when considered
that this disease is totally preventable through active or passive
immunization and that Outbreaks need not occur if responsible preventive
measures are taken.
If you have
been vaccinated for Hepatitis A some of the blood tests may result positive
indicating immunity and not an infection.
Hepatitis A is a liver disease caused
by the Hepatitis A virus.
According to Centers for Disease
Control and Prevention, It is estimated that there are between 125,000 and 200,000
total infections per year in the United States,84,000
to 134,000 of the total infections will be with symptoms of hepatitis
A.
Hepatitis A (HAV) is transmitted primarily through oral contact with
feces (oral-fecal contact). This includes contaminated food or water sources
and sexual contact, especially oral-anal sex.
HAV has on rare occasions been transmitted by blood. The presence of
virus in the blood occurs with the onset of infection and is thought to be
short-lived.
Most adults infected with HAV usually do develop some symptoms. Symptoms
may develop about 15-50 days after exposure; the average is 28 days. These
may include:
Low-grade fever
Malaise (feeling of
ill-health)
Loss of
appetite
Nausea
Abdominal discomfort
Dark-colored urine
Jaundice (yellowing of the
skin and eyes)
Sexual prevention:
Abstinence (not having sex).
Latex condoms for oral sex
(recommended).
Moisture barriers, like
household plastic wraps or dental dams, may be suggested to reducing risk
from oral-anal sex.
There is no accepted treatment for HAV. Supportive care is recommended,
usually guided by symptoms. Once recovered, an individual is immune and will
not get hepatitis A again.
As part of good partner communication, deciding to use latex condoms and
moisture barriers during sex helps reduce the risk of transmitting a
sexually transmitted disease. HAV can be transmitted through oral-anal sex
so it is recommended to always use safer sex methods to reduce the risk of
transmission.
Vaccination:
HAV is preventable by vaccination. A new combination vaccine called
Twinrix has been approved for protection from both HAV and HBV in persons 18
and older. It reduces the total number of injections for vaccination from
both viruses from five to three. This two-dose series given at least six
months apart, provides pre-exposure protection from HAV infection in
children aged 2 years or older and in adults. Vaccination against HAV is
recommended for those who are at risk of infection.
People who have been exposed to hepatitis A should talk with their health
care provider about a post-exposure immune globulin (IG) injection.
HEPATITIS B
Hepatitis B (HBV) is a serious viral infection of the liver.
It is estimated that 1 to
1.25 million people in the United States have chronic Hepatitis B.
There are an estimated
140,000 to 320,000 new Hepatitis B infections each year in the United
States.
Hepatitis B can cause
chronic infection, cirrhosis (scarring) of the liver, liver cancer, liver
failure and death.
Hepatitis B is
preventable through vaccination.
HBV is found in transmittable levels in body fluids including:
Semen
Vaginal secretions
Saliva
Blood
HBV may be
transmitted:
Sexually (having
unprotected sex with an infected person)
Intravenously
(sharing injecting drug needles or paraphernalia with an infected person)
Neonatally
(mother-to-child if the mother is infected with HBV)
HBV may also be
transmitted in rare cases:
Horizontally (oral
exposure to infected secretions such as saliva). Saliva can be a means of
transmission through bites; however, other types of exposure to saliva,
including kissing, are unlikely ways of transmission.
Risk of transmission
from blood transfusion is currently low in the United States since blood
banks screen donated blood that appears to be infected.
What are the signs or symptoms of Hepatitis B?
Many adults have few or no symptoms. When symptoms are present they may
include:
Anorexia (loss of
appetite)
Malaise
Nausea and vomiting
Abdominal pain
Dark urine
Jaundice (yellowing
of the skin and eyes)
Rash or arthritis may
occur during the prodromal or early acute stage.
Your health care provider
can confirm HBV by using a special blood test to detect HBV particles or
antibodies in the blood.
Babies born to infected
mothers should get blood tests at aged 9 to 15 months to be certain that the
vaccine worked well and that the mother did not pass HBV to her baby during
birth.
Reducing the risk:
Hepatitis B is
preventable through vaccination. Since hepatitis D can only co-exist with
hepatitis B, getting vaccinated against hepatitis B also protects you
against hepatitis D.
The HBV vaccine is
given in a series of three doses.
A new combination
vaccine called Twinrix has been approved for protection from both HAV and
HBV in persons 18 and older. It reduces the total number of injections for
vaccination from both viruses from five to three.
The first and
second doses must be given at least one month apart.
The first and third
doses must be given at least 4 months apart.
If a dose is
missed, it should be given as soon as possible.
The series should
not be restarted if a dose is missed.
Routine booster
doses of the HBV vaccine are NOT currently recommended.
Consult your health
care provider for more information about the HBV vaccine and if it is
right for you.
HIV can impair the
response to the hepatitis vaccine.
Sexual prevention:
Latex condoms are
effective prevention during vaginal, oral and anal sex by reducing contact
with infected bodily fluids (semen, vaginal secretions and blood).
Abstinence and
mutual monogamy also offer a high level of protection.
Hepatitis B can cause:
Chronic infection
Cirrhosis
(scarring) of the liver
Liver cancer
Death
The best news is that
hepatitis B is preventable through vaccination. A person can choose to be
vaccinated and not have to worry.
If you have an acute or chronic hepatitis B infection then you need to talk
to your partner about it so they can decide what option is best for them to
prevent getting infected.
If you find out you have been exposed to hepatitis B, consult your health
care provider as soon as possible to discuss your best options to help
prevent infection.
HEPATITIS C
Up to 90 percent of those
infected with the hepatitis C virus (HCV) have no symptoms at all
It ranks second only to
alcoholism as a cause of liver disease and is the leading reason for liver
transplants in the United States.
There is currently no
vaccine for hepatitis C.
In many cases, symptoms may
not appear for up to 30 years.
An estimated 3 percent of the world's population — more
than 170 million people — carry a mysterious virus that silently attacks
their livers, often without their knowledge. That's because up to 90 percent
of those infected with the hepatitis C virus (HCV) have no symptoms at all.
In fact, most people don't know they have the disease until decades later
when liver damage shows up during routine medical tests. Sometimes people
may learn they have hepatitis C when they try to donate blood, because blood
banks now routinely screen for the virus.
The
liver — which weighs between 3 and 4 pounds — is the largest and most
complex internal organ in your body. It sits behind your lower ribs on the
right side of your abdomen and performs a variety of crucial functions —
including detoxifying harmful substances, purifying your blood and
manufacturing vital nutrients.
Hepatitis C is one of six currently identified
hepatitis viruses — the others are A, B, D, E and G. All cause the liver to
become inflamed, which interferes with its ability to function. Hepatitis C
is generally considered to be among the most serious of these viruses.
In many cases, HCV leads to chronic liver diseases
such as cirrhosis — irreversible and potentially fatal scarring of the liver
— liver cancer or liver failure. It ranks second only to alcoholism as a
cause of liver disease and is the leading reason for liver transplants in
the United States.
Although vaccines are used for hepatitis A and B,
there is currently no vaccine for hepatitis C. In addition, standard
treatments for HCV are not universally effective, so the search for new
treatments is ongoing.
Normally, HCV produces no symptoms in its earliest
stages. If you do have symptoms, they'll generally be mild and flulike. They
include:
Slight fatigue
Nausea or poor appetite
Muscle and joint pains
Tenderness in the area of the liver
Even if you develop chronic hepatitis from the
hepatitis C virus, you may have few, if any, symptoms. In many cases,
symptoms may not appear for up to 30 years. Sometimes, though, you may
experience one or more of the following:
Fatigue
Lack of appetite
Nausea and vomiting
Persistent or recurring yellowing of your skin
and eyes (jaundice)
Low-grade fever
Hepatitis C can cause damage to your liver even if
you don't have symptoms. You're also able to pass the virus to others
without having any symptoms yourself. That's why it's important to be tested
if you think you've been exposed to hepatitis C or you engage in behavior
that puts you at risk.