Trichomonas Vaginalis RNA Test (Males)

What is Trichomonas vaginalis RNA Test for males?

Trichomonas vaginalis is a single celled parasite pear shaped with a characteristic undulating membrane and is highly motile. Since there is no cyst stage, Trichomonas vaginalis does not survive long outside the host.

This organism is considered one of the most common curable, sexually transmitted infections (STI) in the United States. Some studies suggest that T. vaginalis is more prevalent than Chlamydia trachomatis. Over seven million cases of T. vaginalis are estimated to occur annually in both males and females. The actual number of cases may be underestimated since 1) infection with Trichomonas vaginalis is not a reportable disease in the U.S.; 2) a significant number of cases are asymptomatic (10 to 50%); and 3) most tests (excluding the test we offer which is a transcription mediated amplification [TMA]) are not sensitive enough to detect the presence of this parasite.

Trichomonas Vaginalis RNA Test  – Males        $109.00

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Trichomonas infections are harbored in the urogenital tract in females and may result in vaginitis, cervicitis, and urethritis. A significant number of infected females will have copious urogenital discharge along with small hemorrhagic lesions. Complications in pregnant women include premature labor, low-birth-weight offspring, premature rupture of membranes, and post-abortion or post-hysterectomy infections. Asymptomatic infections can also occur in females.

Infections in men are predominately asymptomatic. These asymptomatic male carriers serve as a reservoir for transmission to women during sexual intercourse. The most common symptom of a trichomonas infection in men is burning on urination and discharge. Infection with this organism may result in chronic prostatitis and may contribute to infertility. Trichomonas infections have also been implicated as being a cofactor for HIV transmission.

How accurate is the Trichomonas vaginalis RNA Test for males?

The Trichomonas vaginalis RNA Test is the most sensitive and specific assay available for detecting T vaginalis in clinical samples. The sensitivity of this assay approaches 100% when using vaginal and endocervical swabs and is slightly less sensitive (90% to 95%) when using urine samples. Since TMA detects rRNA targets (up to one million targets per T. vaginalis trophozoite), this assay can easily detect down to one organism per sample. Specificity of the T vaginalis TMA assay approaches 100%.

Other Trichomonas vaginalis assays are less sensitive. One of the most common assays used in clinical practice to detect trichomonas is the microscopic examination of a wet mount. The test is inexpensive, but does require an experienced microscopist to detect the presence or absence of the motile trophozoites. Though highly specific, the test is much less sensitive (50% to 60%) as compared to TMA. Trichomonas culture is more sensitive (up to 75%) than direct microscopy, but requires several days for the organisms to grow before being detected by microscopic exam of the specific trichomonas culture broth.
The drugs of choice for treating trichomonas infections are either metronidazole or tinidazole. All sexual partners of infected patients should be treated. Treatment failures are most commonly due to lack of compliance in taking the drugs. True metronidazole resistance has been described and may be increasing. Patients should always discuss specific treatment options with their doctors.

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